BOTTOM LINE: Are Cats Right- or Left-Handed? The truth is that 42% of cats are ambidextrous, 38% favor their left paws, and 20% favor their right. Humans aren’t the only species that favors their left or right hands. Cats also have a preference, although a large percentage can use both paws equally well. About 42% of cats are ambidextrous, 38% favor their left paws, and 20% favor their right paws.